Pain Management Compounding
Pain is an unpleasant sensation, but it acts as an alarm system that can protect us from further injury. Things feel unpleasantly painful so your body will quickly take steps to remove the source of the damage. It is just one of many survival mechanisms of the body.
However, there are many instances where pain seems to serve no function. It does not alert us to avoid injury or further injury and is just painful. Of the several different types of pain, most seem to have no protective purpose or its value as a protective warning system is over but the pain continues.
Be it sharp or dull, intermittent or constant, acute or chronic, pain affects overall health and wellbeing.
Importance of Controlling Pain
Continuous, unrelieved pain can affect you physically and psychologically, can also have a psychological adverse effect on your family and/or loved ones.
It is not just the sensation of pain your body is dealing with, what is often overlooked is that pain has physically harmful effects.
Pain causes stress. Your body reacts by releasing an excessive amount of hormones, ultimately resulting in carbohydrate, protein, and fat destruction; poor glucose use; and other harmful effects. This reaction combined with inflammatory processes can produce weight loss, tachycardia, increased respiratory rate, fever, shock, and death.1 Unrelieved pain prolongs the stress response, which can suppress the immune system and result in infection and poor wound healing. Sympathetic activation can have negative effects on the cardiovascular, gastrointestinal, and renal systems
Unrelieved pain may be especially harmful for patients with metastatic cancers. Stress and pain can suppress immune functions, including the natural killer (NK) cells that play a role in preventing tumor growth and controlling metastasis.2, 3 Further, management of perioperative pain is probably a critical factor in preventing surgery-induced decrease in resistance against metastasis.
Unrelieved acute pain can result in chronic pain at a later date. Thus, pain now can cause pain later. If acute shingles pain is not treated aggressively, it is believed to increase the risk of postherpetic neuralgia
Continuous, unrelieved pain also affects your psychological state and your family members’. Common psychological responses to pain include anxiety and depression. The inability to escape from pain may create a sense of helplessness and even hopelessness, which may expose you to a more chronic depression. Patients who have experienced inadequate pain management may be reluctant to seek medical care for other health problems. Read more on the Importance of Controlling Pain: https://www.ncbi.nlm.nih.gov/books/NBK2658/
The Basic Types of Pain
There are two well-recognized broad categories of pain:
- Nociceptive pain arises from various kinds of trouble in tissues, reported to the brain by the nervous system. This is the most common type of pain everyone is familiar with, this range from bee stings and burns and toe stubs to repetitive strain injury, nausea, tumours, and inflammatory arthritis. Nociceptive pain typically changes with movement, position, and load.
- Neuropathic pain arises from damage to the central or peripheral nervous system itself, either from disease, injury, or pinching. The simplest neuropathies are mechanical insults, like hitting your funny bone or sciatica, but this is a big category: anything that damages neurons, from multiple sclerosis to chemotherapy to alcoholism to phantom limb pain. It’s often stabbing, electrical, or burning, but nearly any quality of pain is possible. Unfortunately, it’s also more likely to lead to chronic pain: nerves don’t heal well.
Obviously, these kinds of pain can overlap. Some medical problems, like injuries, can affect both nerves themselves and other tissues, causing both kinds of pain. However, it’s surprising how little overlap there is: look at any list of the most painful conditions and they all fit pretty clearly into one category or the other.
Some common kinds of pain are not a great fit for either of the two official categories. The canonical example is the pain of fibromyalgia. Other major examples:
- complex regional pain syndrome(CRPS)
- nonspecific chronic low-back pain
- irritable bowel syndrome[Mayo] and other functional visceral pain disorders
- conditions that begin as nociceptive pain, like osteoarthritis, but then go into a hellish downward spiral of sensitization
Migraine? Still tough to classify! Some experts consider it a major category of its own, parallel to nociceptive and neuropathic pain, but it’s probably just a complicated neuropathy.
Use our FREE Pain assessment tool to help you better understand your pain Click here
Treating pain in a conservative and comprehensive fashion is key to regaining a more functional state. Pain management requires a delicate balance targeted towards treating the symptoms of pain while minimizing potential adverse effects of therapy such as rebound pain, addiction and Medication side effects
Compounded pain medicines have become a mainstay in treating complex pain. Individualized pain therapy, delivered in the right vehicle and dosage form, can be the difference between minor relief and getting back to doing what you love.
Compounded Pain Cream
COMPOUNDED PAIN CREAM is specifically designed to target and treat the site of pain with customizable formulations, while avoiding many of the complications common to other pain treatment methods. Pain Cream provides a flexible, convenient, and effective solution for a variety of pain-related conditions.
PAIN CREAMS ARE DESIGNED to administer high concentrations of pain medication directly onto the site of pain for targeted relief. Furthermore, our pharmacists can work with your doctor to create a custom formulation, designed to meet your unique needs. As a result, you get the combined benefits of precise dosing, personalized treatment, and the combined effect of multiple ingredients working together for optimal pain relief.
Fewer Risks & Side Effects
BECAUSE OUR PAIN FORMULATIONS are applied topically, they nearly do not circulate throughout the entire body. This means you have powerful pain medication where you need it and less where you don’t. As a result, Pain Creams are less likely to interact with other medications being taken and cause fewer side effects than other pain medications. Finally, since Pain Cream is minimally absorbed throughout the entire body, the risk of dependence and addiction is virtually eliminated.
Active Ingredients in COMPOUNDED PAIN CREAM FORMULATIONS
Anesthetic. Treats pain by blocking electrical signals in the brain and spine.
Tricyclic antidepressant. Inhibits serotonin reuptake, suppressing pain signals in the central nervous system.
Muscle relaxant / antispasmodic. Helps reduce pain by relaxing muscles. Since topical use causes much less systemic absorption, the typical side effects (drowsiness, increased urination, mental confusion, constipation and fatigue) are usually not seen.
Local anesthetic. Can be used to treat neuropathic pain by blocking nerve signals.
Antihypertensive. Used to treat neuropathic pain.
Muscle relaxant. Helps control muscle spasms and tightness. A common side effect of this medication when taken orally is drowsiness, but this risk is reduced with transdermal medication.
Antiviral. Treats viral infections, like shingles, by inhibiting the growth and proliferation of virus cells.
Anti-inflammatory (NSAID). Helps reduce inflammation and pain. Transdermal application reduces the risk of side effects, such as GI upset, and lowers the possibility of stomach ulceration. The FDA requests that physicians measure liver function periodically in patients receiving long-term therapy with diclofenac.
Anticonvulsant. Works by three mechanisms to treat neuropathic pain (pain typically caused by damaged or misfiring nerve fibers). Best combined with ketamine for maximum synergistic effect.
Tricyclic antidepressant. Treats neuropathic pain by acting on serotonin and norepinephrine in the nervous system.
Anti-inflammatory (NSAID). Helps reduce hormones which cause inflammation and pain. There is extensive research on transdermal delivery of ketoprofen.
Anti-inflammatory (NSAID). Reduces pain, inflammation, and fever. Used short-term to treat moderate to severe pain of the skin, muscles, and soft tissues.
Topical Anesthetic. Helps reduce pain. The most common transdermal side effects are tingling and numbness at the site of application.
Topical anesthetic. Provides local pain relief by deadening nerves at site of application.
The following is a list of some of the pain conditions for which we commonly compound medications:
- Ankle Pain
- Back Pain
- Burning Foot Syndrome
- Carpal Tunnel Syndrome
- CRPS (Chronic Regional Pain Syndrome)
- Diabetic Neuropathy
- Foot Pain
- Head, Neck, and Facial Pain
- Knee Pain
- Muscle Spasms
- Neuropathic Pain
- Post Herpetic Neuralgia
- Shoulder Pain
- Tennis Elbow
- TMJ/TMD (Temporomandibular Disorders)
We work together with Doctors and patients to solve problems by customizing medications that meet the specific needs of each individual.